Philosophy Mondays: Human-AI Collaboration
Today's Philosophy Monday is an important interlude. I want to reveal that I have not been writing the posts in this series entirely by myself. Instead I have been working with Claude, not just for the graphic illustrations, but also for the text. My method has been to write a rough draft and then ask Claude for improvement suggestions. I will expand this collaboration to other intelligences going forward, including open source models such as Llama and DeepSeek. I will also explore other moda...
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Web3/Crypto: Why Bother?
One thing that keeps surprising me is how quite a few people see absolutely nothing redeeming in web3 (née crypto). Maybe this is their genuine belief. Maybe it is a reaction to the extreme boosterism of some proponents who present web3 as bringing about a libertarian nirvana. From early on I have tried to provide a more rounded perspective, pointing to both the good and the bad that can come from it as in my talks at the Blockstack Summits. Today, however, I want to attempt to provide a coge...
Philosophy Mondays: Human-AI Collaboration
Today's Philosophy Monday is an important interlude. I want to reveal that I have not been writing the posts in this series entirely by myself. Instead I have been working with Claude, not just for the graphic illustrations, but also for the text. My method has been to write a rough draft and then ask Claude for improvement suggestions. I will expand this collaboration to other intelligences going forward, including open source models such as Llama and DeepSeek. I will also explore other moda...
Intent-based Collaboration Environments
AI Native IDEs for Code, Engineering, Science
Web3/Crypto: Why Bother?
One thing that keeps surprising me is how quite a few people see absolutely nothing redeeming in web3 (née crypto). Maybe this is their genuine belief. Maybe it is a reaction to the extreme boosterism of some proponents who present web3 as bringing about a libertarian nirvana. From early on I have tried to provide a more rounded perspective, pointing to both the good and the bad that can come from it as in my talks at the Blockstack Summits. Today, however, I want to attempt to provide a coge...
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Halloween is coming up. But if you really want to scare yourself, I suggest you read this interview with an associate director at the CDC about the “end of antibiotics.” Essentially we are not only seeing more bacteria that are resistant to absolutely every medication we have but these bacteria are now spreading outside of hospitals and are more rapidly sharing their genetic antibacterial immunity with other much more common bacteria.
In the meantime there are no (as in zero) new antibiotics in the drug pipeline. I for one am not inclined to say let’s wait for some startup to figure out that this might be an opportunity. Instead this is a perfect example of a massive market failure and exactly the kind of situation in which we need government to intervene. So far unfortunately we have not seen any action by politicians despite experts using words such as “nightmare” to describe the present situation.
So one other suggestion: if you are a newly minted billionaire or know one, this might be a good place to spend some serious money. Full drug development costs a fortune, but we need to put a lot of new ideas into the pipeline if we want to find something that works.
Halloween is coming up. But if you really want to scare yourself, I suggest you read this interview with an associate director at the CDC about the “end of antibiotics.” Essentially we are not only seeing more bacteria that are resistant to absolutely every medication we have but these bacteria are now spreading outside of hospitals and are more rapidly sharing their genetic antibacterial immunity with other much more common bacteria.
In the meantime there are no (as in zero) new antibiotics in the drug pipeline. I for one am not inclined to say let’s wait for some startup to figure out that this might be an opportunity. Instead this is a perfect example of a massive market failure and exactly the kind of situation in which we need government to intervene. So far unfortunately we have not seen any action by politicians despite experts using words such as “nightmare” to describe the present situation.
So one other suggestion: if you are a newly minted billionaire or know one, this might be a good place to spend some serious money. Full drug development costs a fortune, but we need to put a lot of new ideas into the pipeline if we want to find something that works.
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